Opportunity Information: Apply for RFA TR 16 021

The Coordination Center for the CTSA Program (U24) funding opportunity (RFA TR 16 021) is a National Institutes of Health cooperative agreement intended to fund a single Coordination Center that serves as the organizing and operational backbone for the Clinical and Translational Science Award (CTSA) Program. The CTSA Program is a nationwide effort designed to strengthen and speed up translational and clinical research, improve the overall research process, and ultimately help move treatments and health innovations to patients faster. As the CTSA Program continues to evolve into a more integrated national consortium of medical research institutions, the Coordination Center is expected to make that consortium work smoothly by enabling consistent collaboration across the CTSA "hubs" and supporting shared goals, shared methods, and shared infrastructure.

At its core, the Coordination Center is meant to facilitate collaboration and consortium-wide activities rather than conduct a single local research project. The FOA emphasizes the need for an "environment of excellence," meaning a high-performing operational center with strong leadership, reliable processes, and the capacity to support a complex national network. A major part of the role is to develop and apply innovative approaches to how the CTSA Program collects, analyzes, uses, and shares many different types of data. This is not framed as data management for its own sake, but as data-driven strategic management of the CTSA Program: using information to understand how the consortium is functioning, identify gaps and opportunities, track progress, and help guide decision-making at a program level.

In addition to data capabilities, the Coordination Center is expected to build and maintain the collaboration, coordination, and communication infrastructure that allows the consortium to operate effectively. That includes supporting scientific activities across sites, coordinating training and career development efforts, enabling governance processes, and providing logistical support for workgroups and other cross-hub teams. Practically, this points to responsibilities such as organizing meetings and consortium events, supporting communications across many institutions, maintaining shared platforms or tools for collaboration, helping standardize approaches when appropriate, and ensuring that the different moving parts of the CTSA consortium can align and execute together.

The award mechanism is a cooperative agreement (U24), which typically indicates substantial NIH involvement during the project period compared to a standard grant. In other words, the Coordination Center is expected to work closely with NIH program leadership in an ongoing, collaborative way, and to remain responsive to consortium priorities as they develop. The funding opportunity sits in the health category and is administered under the U.S. Department of Health and Human Services through NIH.

Eligibility is broad and includes many organization types that could plausibly operate a national coordination function. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other entities as described in the FOA's additional eligibility language. This wide eligibility suggests the program is focused on capability and infrastructure rather than restricting applicants to a narrow institutional type.

Key administrative details from the notice include a creation date of November 2, 2016, with an original closing date of January 31, 2017. The award ceiling listed is $3,000,000, and the opportunity anticipated making 1 award, consistent with the concept of a single Coordination Center serving the whole CTSA Program.

Overall, this FOA is about strengthening the national CTSA consortium by funding one central entity to connect the hubs, run the shared operations, modernize how consortium data are gathered and used for strategic oversight, and provide the communication and coordination systems needed to support scientific collaboration, training activities, governance, and workgroup productivity across the program.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Coordination Center for the CTSA Program (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.350.
  • This funding opportunity was created on Nov 02, 2016.
  • Applicants must submit their applications by Jan 31, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)

What is the Coordination Center for the CTSA Program (U24) funding opportunity?

This funding opportunity (RFA TR 16 021) is a National Institutes of Health (NIH) cooperative agreement intended to support a single Coordination Center for the Clinical and Translational Science Award (CTSA) Program. The Coordination Center functions as the organizing and operational backbone for the nationwide CTSA consortium.

Which organization administers this opportunity?

The opportunity is administered by the U.S. Department of Health and Human Services (HHS) through the National Institutes of Health (NIH).

What is the main purpose of the CTSA Program?

The CTSA Program is a nationwide effort designed to strengthen and accelerate translational and clinical research, improve the overall research process, and help move treatments and health innovations to patients faster.

What is the main purpose of the Coordination Center within the CTSA Program?

The Coordination Center is intended to make the CTSA consortium work smoothly by enabling consistent collaboration across CTSA hubs and supporting shared goals, shared methods, and shared infrastructure across the national network.

Is this grant intended to fund a local research project at a single institution?

No. The Coordination Center is meant to facilitate collaboration and consortium-wide activities rather than conduct a single local research project.

How many awards are expected to be made under this opportunity?

The opportunity anticipates making 1 award, consistent with the intent to fund a single Coordination Center serving the full CTSA Program.

What is the award mechanism for this opportunity?

The award mechanism is a cooperative agreement (U24).

What does a cooperative agreement (U24) imply about NIH involvement?

A U24 cooperative agreement typically indicates substantial NIH involvement during the project period compared to a standard grant. Under this structure, the Coordination Center is expected to work closely with NIH program leadership on an ongoing basis and remain responsive to evolving consortium priorities.

What does the FOA mean by an "environment of excellence"?

The FOA emphasizes an "environment of excellence" in the sense of a high-performing operational center with strong leadership, reliable processes, and the capacity to support a complex national network of medical research institutions.

What kinds of data responsibilities are expected of the Coordination Center?

A major expectation is to develop and apply innovative approaches to how the CTSA Program collects, analyzes, uses, and shares many different types of data. This is framed as data-driven strategic management of the CTSA Program, using information to understand consortium functioning, identify gaps and opportunities, track progress, and guide program-level decision-making.

Is the data work described mainly routine data management?

No. The FOA frames data activities as strategic oversight and management of the program (for example, understanding how the consortium is functioning and tracking progress), rather than data management for its own sake.

What collaboration and communication functions is the Coordination Center expected to provide?

The Coordination Center is expected to build and maintain the collaboration, coordination, and communication infrastructure that allows the consortium to operate effectively across many institutions and hubs.

What types of consortium activities may the Coordination Center support?

Based on the FOA description, the Coordination Center may support scientific activities across sites, coordinate training and career development efforts, enable governance processes, and provide logistical support for workgroups and other cross-hub teams.

What are examples of practical responsibilities the Coordination Center may carry out?

Practical responsibilities described include organizing meetings and consortium events, supporting communications across many institutions, maintaining shared platforms or tools for collaboration, helping standardize approaches when appropriate, and ensuring the different moving parts of the CTSA consortium align and execute together.

Who is eligible to apply?

Eligibility is broad. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other entities as described in the FOA's additional eligibility language.

Does the wide eligibility suggest anything about what NIH is prioritizing?

Yes. The wide eligibility suggests the program is focused on capability and infrastructure for national coordination rather than limiting applicants to a narrow institutional type.

What is the funding category for this opportunity?

The opportunity is in the health category.

What is the award ceiling listed for this opportunity?

The award ceiling listed is $3,000,000.

When was this opportunity created and when did it close?

The notice lists a creation date of November 2, 2016, and an original closing date of January 31, 2017.

How does this opportunity relate to the evolving CTSA consortium model?

As the CTSA Program evolves into a more integrated national consortium, the Coordination Center is expected to support consistent collaboration across hubs and provide the shared operational structure needed for the consortium to function as a unified network.

What kinds of consortium-wide outcomes is the Coordination Center expected to enable?

The FOA describes outcomes centered on stronger collaboration across hubs, improved coordination and communication, modernized and more strategic use of consortium data, and smoother execution of shared scientific, training, governance, and workgroup activities across the CTSA Program.

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