Opportunity Information: Apply for PA 20 198
The Mentored Quantitative Research Development Award (K25), listed as PA 20-198, is a National Institutes of Health (NIH) career development grant designed to bring experienced quantitative scientists and engineers into NIH-relevant biomedical, behavioral, and health-related research. Its core aim is to support productive professionals whose prior work has not been primarily centered on health and disease, and to help them pivot their established quantitative expertise toward research questions that matter to human health. In practical terms, the program is meant for people trained in fields like mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry, and engineering who can contribute advanced analytic or technical approaches to health research but need structured mentored time and training to fully integrate into NIH’s research ecosystem.
A key feature of the K25 is the emphasis on mentored career development. The award is structured to provide “protected time,” meaning dedicated effort that is set aside specifically for supervised study, skills development, and mentored research rather than being consumed by unrelated duties. The expectation is that the applicant will work closely with one or more mentors and follow a deliberate career development plan that builds biomedical or clinical research fluency while applying quantitative methods to NIH-relevant problems. Because this specific parent opportunity is labeled “Independent Basic Experimental Studies with Humans Required,” it signals that the supported research is expected to include basic experimental work involving human participants (as NIH defines those studies), rather than being limited to purely theoretical, animal-only, or exclusively secondary analyses. Applicants typically need to align their proposed research and training activities to this human-focused experimental requirement.
The opportunity is categorized as a discretionary grant program and falls within broad public-purpose areas including education and health. It is associated with multiple CFDA (Assistance Listing) numbers: 93.113, 93.121, 93.173, 93.273, 93.279, 93.865, and 93.866, reflecting that NIH institutes and centers across different mission areas can potentially support K25 applicants when the proposed work matches their priorities. The notice lists an original closing date of 2024-05-07, and while no award ceiling or expected number of awards is specified in the provided data, applicants generally should interpret that as meaning budgets and award counts may vary by NIH institute, the applicant’s career stage and needs, and annual appropriations.
Eligibility is broad at the organizational level and includes many common U.S.-based applicant types such as public and private institutions of higher education, state and local governments, independent school districts, special district governments, federally recognized tribal governments, tribal organizations that are not federally recognized, public housing authorities/Indian housing authorities, nonprofits with or without 501(c)(3) status (when not classified as institutions of higher education), for-profit organizations (other than small businesses), and small businesses. The announcement also explicitly highlights additional eligible applicant categories that NIH often encourages to apply, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. At the same time, there are clear geographic limitations: non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply. However, “foreign components” as defined by the NIH Grants Policy Statement are allowed, which generally means a U.S. applicant organization may include certain international elements within an otherwise domestic application when justified and permitted under NIH policy.
Overall, this K25 opportunity is best understood as a bridge award for quantitatively trained researchers who already have strong technical credentials but need a structured, mentored pathway into health and disease research, including hands-on experience with human-focused experimental studies. The award’s value is in buying time for training, mentorship, and NIH-relevant research productivity, so that recipients can reposition their careers toward sustained, independent contributions at the intersection of quantitative science and human health.Apply for PA 20 198
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.273, 93.279, 93.865, 93.866.
- This funding opportunity was created on 2020-05-07.
- Applicants must submit their applications by 2024-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 20 198) also looked into and applied for these:
| Funding Opportunity |
|---|
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 204 Funding Number: PA 20 204 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 201 Funding Number: PA 20 201 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) Apply for PA 20 202 Funding Number: PA 20 202 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Emergency Awards: RADx-UP Coordination and Data Collection Center (CDCC) (U24 Clinical Trial Optional) Apply for RFA OD 20 013 Funding Number: RFA OD 20 013 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Tools for Germline Gene Editing in Marmosets (U01 - Clinical Trial Not Allowed) Apply for RFA DA 21 006 Funding Number: RFA DA 21 006 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Fertility Status as a Marker for Overall Health (R01 Clinical Trial Optional) Apply for PAR 20 281 Funding Number: PAR 20 281 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Fertility Status as a Marker for Overall Health (R21 Clinical Trial Not Allowed) Apply for PAR 20 282 Funding Number: PAR 20 282 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Centers to Advance Research in Endometriosis (CARE) (P01 Clinical Trial Not Allowed) Apply for RFA HD 21 002 Funding Number: RFA HD 21 002 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| NIH Blueprint for Neuroscience Research: Functional Neural Circuits of Interoception (R01, Clinical Trial Not Allowed) Apply for RFA AT 21 003 Funding Number: RFA AT 21 003 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $375,000 |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required) Apply for PAR 21 039 Funding Number: PAR 21 039 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience Research: Tools and Technologies to Explore Nervous System Biomolecular Condensates (R21 Clinical Trial Not Allowed) Apply for RFA DA 22 008 Funding Number: RFA DA 22 008 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Building Interdisciplinary Research Careers in Women's Health Program (BIRCWH) (K12 Clinical Trial Optional) Apply for RFA OD 21 006 Funding Number: RFA OD 21 006 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $600,000 |
| NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) Apply for RFA NS 21 012 Funding Number: RFA NS 21 012 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 21 261 Funding Number: PA 21 261 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional) Apply for PAR 21 303 Funding Number: PAR 21 303 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience Research Short Courses in Neurotherapeutics Development (R25 Clinical Trial Not Allowed) Apply for RFA NS 21 025 Funding Number: RFA NS 21 025 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $250,000 |
| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 22 060 Funding Number: PAR 22 060 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $375,000 |
| Implementation Research to Reduce Noncommunicable Disease (NCD) Burden in Low- and Middle-Income Countries (LMICs) and Tribal Nations During Critical Life Stages and Key Transition Periods (R01 Clinical Trial Optional) Apply for PAR 22 132 Funding Number: PAR 22 132 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) Apply for PAR 22 160 Funding Number: PAR 22 160 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Apply for PAR 22 106 Funding Number: PAR 22 106 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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