Opportunity Information: Apply for HT9425 24 TERP TRA
The Toxic Exposures Translational Research Award (TERP TRA), Funding Opportunity Number HT9425 24 TERP TRA, is a discretionary grant program run by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA). It sits in the Science and Technology and other Research and Development category (CFDA 12.420) and is aimed squarely at moving military-relevant toxic exposure research out of the purely academic or exploratory stage and closer to real-world clinical use. In practical terms, the program is designed to help bridge the gap between what researchers are learning about toxic exposures affecting service members and what clinicians can actually use to prevent, diagnose, treat, or manage related health problems.
The core purpose of the FY24 TERP TRA is to fund translational research that accelerates the path from promising scientific ideas to clinical applications. The opportunity is not framed as basic science for its own sake, and it is not limited to clinical trials alone. Instead, it emphasizes research that connects the two ends of the pipeline: basic science findings and clinical observations, with the expectation that each side informs the other. Competitive projects should clearly show how the work will produce something that can credibly advance toward health care products, medical interventions, enabling technologies, and/or clinical practice guidelines. The intent is to generate outcomes that are closer to implementation in health care settings rather than stopping at discovery or early proof-of-concept without a plan to translate those results.
A key expectation is evidence of "reciprocal transfer" between basic and clinical science. That means proposals should not treat laboratory work and clinical insights as separate silos. The research plan should demonstrate how clinical observations can shape laboratory experiments (for example, by focusing on exposure scenarios, biomarkers, or outcomes seen in real patients), and how basic science results will feed back into clinically relevant decisions (such as refining diagnostic criteria, identifying patient subgroups, informing intervention design, or supporting guideline development). The program also allows for the use of New Approach Methodologies (NAMs), which generally refers to newer experimental and analytical approaches that can complement or, in some contexts, reduce reliance on traditional models. This can include advanced in vitro systems, computational models, high-throughput screening, or other modern methods that strengthen the translation of exposure science to clinical insight.
Eligibility is listed as unrestricted, meaning the opportunity is broadly open to applicants rather than limited to a narrow set of institution types. The agency anticipates making about six awards under this announcement. The original application closing date is November 7, 2024. While an award ceiling is referenced in the source data, a specific maximum dollar amount is not provided in the details shared here, so applicants would need to refer to the full announcement for budget limits, performance period expectations, and any cost constraints or match requirements. Overall, the TERP TRA is best understood as a funding mechanism for teams that can credibly connect military-related toxic exposure questions to tangible, clinically meaningful outputs and can demonstrate a clear, two-way integration of bench and bedside evidence throughout the project.Apply for HT9425 24 TERP TRA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Toxic Exposures Translational Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2024-06-26.
- Applicants must submit their applications by 2024-11-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted.
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Frequently Asked Questions (FAQs): Toxic Exposures Translational Research Award (TERP TRA)
What is the Toxic Exposures Translational Research Award (TERP TRA)?
The Toxic Exposures Translational Research Award (TERP TRA) is a discretionary government grant program focused on translational research related to military-relevant toxic exposures. It is intended to move research beyond purely academic discovery and closer to real-world clinical use for service member health.
What is the Funding Opportunity Number for this grant?
The Funding Opportunity Number (FON) is HT9425 24 TERP TRA.
Which agency runs this funding opportunity?
The program is run by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA).
What category does this opportunity fall under?
This opportunity is in the Science and Technology and other Research and Development category and is associated with CFDA 12.420.
What is the main goal of the FY24 TERP TRA program?
The main goal is to fund translational research that accelerates the path from promising toxic exposure science to clinical applications. The emphasis is on producing outcomes that can credibly advance toward use in health care settings.
Is this funding intended for basic research?
The opportunity is not framed as basic science for its own sake. Projects are expected to connect scientific findings to clinical needs and to show a clear translation plan toward practical clinical outputs.
Is the TERP TRA limited to clinical trials?
No. The program is not limited to clinical trials alone. It supports research that connects basic science and clinical observations, with the expectation that each informs the other.
What kinds of outcomes are considered competitive or desirable?
Competitive projects should show how the work will produce outputs that can credibly advance toward health care products, medical interventions, enabling technologies, and/or clinical practice guidelines, rather than stopping at discovery without a translation plan.
What does "reciprocal transfer" between basic and clinical science mean in this program?
"Reciprocal transfer" means the proposal should integrate laboratory and clinical work in a two-way manner. Clinical observations should shape laboratory experiments (for example, focusing on exposure scenarios, biomarkers, or outcomes seen in real patients), and basic science results should feed back into clinically relevant decisions (such as refining diagnostic criteria, identifying patient subgroups, informing intervention design, or supporting guideline development).
How should applicants demonstrate the bench-to-bedside connection?
Applicants should present a research plan where clinical insights and basic science findings continuously inform each other throughout the project, with a clear path toward practical clinical outputs related to toxic exposures affecting service members.
Are New Approach Methodologies (NAMs) allowed?
Yes. The program allows the use of New Approach Methodologies (NAMs), including modern experimental and analytical approaches that can strengthen translation from exposure science to clinical insight.
What are examples of NAMs mentioned for this opportunity?
Examples mentioned include advanced in vitro systems, computational models, high-throughput screening, and other modern methods that may complement or reduce reliance on traditional models in some contexts.
Who is eligible to apply?
Eligibility is listed as unrestricted, meaning the opportunity is broadly open to applicants and is not limited to a narrow set of institution types.
How many awards does the agency expect to make?
The agency anticipates making about six awards under this announcement.
What is the application closing date?
The original application closing date is November 7, 2024.
Is there a maximum award amount (award ceiling) listed?
An award ceiling is referenced in the source data, but a specific maximum dollar amount is not provided in the information shared here. Applicants would need to refer to the full announcement for exact budget limits.
Where can applicants find details on budget limits, performance period, and cost constraints?
The information provided here indicates those details are not included. Applicants should consult the full funding announcement for budget caps, expected period of performance, any cost constraints, and any match requirements (if applicable).
What types of projects are a good fit for TERP TRA?
Projects are a good fit when they connect military-related toxic exposure questions to tangible, clinically meaningful outputs and clearly integrate clinical and basic science evidence in a two-way, translational manner.
What is the overall intent of this program in practical terms?
The intent is to bridge the gap between what researchers are learning about toxic exposures affecting service members and what clinicians can use to prevent, diagnose, treat, or manage related health problems.
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| Toxic Exposures Investigator-Initiated Research Award Apply for HT9425 24 TERP IIRA Funding Number: HT9425 24 TERP IIRA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| Cooperative Agreement for CESU-affiliated Partner with Rocky Mountain Cooperative Ecosystem Studies Unit Apply for G24AS00415 Funding Number: G24AS00415 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: $225,000 |
| DoD Reconstructive Transplant, Advanced Technology Development Award Apply for HT942524RTRPATDA Funding Number: HT942524RTRPATDA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Reconstructive Transplant, Idea Discovery Award Apply for HT942524RTRPIDA Funding Number: HT942524RTRPIDA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Reconstructive Transplant Research, Investigator-Initiated Research Award Apply for HT942524RTRPIIRA Funding Number: HT942524RTRPIIRA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Agreement for CESU-affiliated Partner with Gulf Coast Cooperative Ecosystem Studies Unit Apply for G24AS00416 Funding Number: G24AS00416 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: $131,500 |
| Study Tour in the United States on Security Research (R&D) and IP Protection for Greek Researchers Apply for PAS ATHENS FY2024 02 Funding Number: PAS ATHENS FY2024 02 Agency: U.S. Mission to Greece Category: Science and Technology and other Research and Development Funding Amount: $100,000 |
| Research on the Science and Technology Enterprise: Indicators, Statistics, and Methods (NCSES S&T) Apply for 24 587 Funding Number: 24 587 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Standardization Center of Excellence Apply for 2024 NIST SCOE 01 Funding Number: 2024 NIST SCOE 01 Agency: National Institute of Standards and Technology Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2025 Department of the Navy (DoN) Historically Black Colleges and Universities/Minority Institutions (HBCU/MI) Program Apply for N0001424SF006 Funding Number: N0001424SF006 Agency: Office of Naval Research Category: Science and Technology and other Research and Development Funding Amount: $525,000 |
| NSF EPSCoR Graduate Fellowship Program Apply for 24 588 Funding Number: 24 588 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $3,180,000 |
| U.S. EMBASSY TO SWITZERLAND AND LIECHTENSTEIN PUBLIC DIPLOMACY SECTION ANNUAL PROGRAM STATEMENT Apply for OFOP0001500 Funding Number: OFOP0001500 Agency: U.S. Mission to Switzerland Category: Science and Technology and other Research and Development Funding Amount: $12,500 |
| Risk Analysis of Biotechnology for the Protection of Environmental Resources Apply for W81EWF 24 SOI 0033 Funding Number: W81EWF 24 SOI 0033 Agency: Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $100,000 |
| Disrupting and Managing Riverine and other Large-Scale Freshwater Harmful Algal Blooms Apply for W81EWF 24 SOI 0032 Funding Number: W81EWF 24 SOI 0032 Agency: Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
| Automated Organization and Analysis of Hydrologic and Infrastructure Data Apply for W81EWF 24 SOI 0034 Funding Number: W81EWF 24 SOI 0034 Agency: Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $75,000 |
| Comprehensive Stranding Investigations for High Priority Marine Mammal Species in the Hawaiian and Mariana Archipelagos, Navy US Pacific Fleet, Pearl Harbor, HI Apply for W9126G 24 2 SOI 3586 Funding Number: W9126G 24 2 SOI 3586 Agency: Fort Worth District Category: Science and Technology and other Research and Development Funding Amount: $3,717,000 |
| Computer and Information Science and Engineering (CISE): Core Programs Apply for 24 589 Funding Number: 24 589 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $12,000,000 |
| Minority Serving Institutions (MSIs) and Historically Black Colleges and Universities (HBCUs) Science, Technology, Engineering and Mathematics (STEM) Consortium Apply for W911SR 24 S 0001 Funding Number: W911SR 24 S 0001 Agency: ACC-APG-Edgewood Category: Science and Technology and other Research and Development Funding Amount: $15,000,000 |
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